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IRCT20121110011421N4 IRCT 2021-07-12 Tehran University of Medical Sciences The effect of Spirulina supplementation on plasma markers of exercise-induced muscle damage The effect of Spirulina supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity in Tekwando athletes: a cross-over trail. 2019-04-09 anticipated 18 Complete https://irct.ir/trial/11692 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Supportive, Other design features: The study is designed as a crossover. The study has two periods with a duration of 21 days. In the first period, group 1 receives spirulina and in the second period receives a placebo. Group 2 receives placebo in the first period and spirulina in the second period. The two study periods are separated by a 14-day washout period, Randomization description: To create random sequences in this study which has two groups, the coin toss method was used. The first group includes people who first receive spirulina and then placebo, and the second group receives first placebo and then spirulina. Coin toss was performed according to the sample size and individuals were randomly assigned to one of the two groups, Blinding description: Supplement and placebo delivered to the two groups are completely similar in appearance and the researcher will be aware of its coding at the end of the study. N/A Exercise-induced muscle damage. This study has two groups. Group 1 receives spirulina in the first period of study and placebo in the second period of study. Group 2 receive placebo in the first period and spirulina in the second period. The two study periods are separated by a 14-day washout period. The duration of receiving spirulina or placebo in the first and second period is 21 days.The spirulina sachet contained 8 g of Spirulina flavored with lemon and mint (Qeshm Island Science and Technology Park by Drotat Setareh Qeshm). The placebo sachet was 8 g starch flour with the same flavor and green food coloring.. Yes - There is a plan to make this available What will be shared: According to the field of study and information received from people, all parts of it have the ability to share data When: Access from the second half of 1400 To whom: All researchers in the field of sport nutrition Conditions: All data obtained can be used for various analyzes Where to obtain: The request should be sent to the e-mail of Dr. Kurosh Djafarian or Arvin Kashani. kdjafarian@tums.ac.ir kashani.arvin@gmail.com How to obtain: After receiving the application and reviewing it by email, it will be sent to the people within 2 working weeks. Comments:
public Arvin kashani
Vesk Ave., 14 street number 31
Tehran Iran (Islamic Republic of) 4545656456 +98 21 4436 6496 kashani.arvin@gmail.com Tehran University of Medical Sciences scientific Kurosh djafarian
Vesal shirazi Ave., SNSD
Tehran Iran (Islamic Republic of) 1417653761 +98 21 8898 4837 kdjafarian@tums.ac.ir Tehran University of Medical Sciences Iran (Islamic Republic of) Male Taekwondo Athletes Taekwondo athletes with experience of at least 3 years Age from 18 to 35 years 18 years 35 years Male Tobacco and drug use in the last year Use of anti-inflammatory drugs in the last three months Follow special and unusual diets in the last three months Consumers of sports supplements in the last three months Having chronic diseases that require a person to take medicine People weighing less than 40 kg Blood donors during the month before the test People with illness or surgery in the last 3 months Rehabilitation This study has two groups. Group 1 receives spirulina in the first period of study and placebo in the second period of study. Group 2 receive placebo in the first period and spirulina in the second period. The two study periods are separated by a 14-day washout period. The duration of receiving spirulina or placebo in the first and second period is 21 days.The spirulina sachet contained 8 g of Spirulina flavored with lemon and mint (Qeshm Island Science and Technology Park by Drotat Setareh Qeshm). The placebo sachet was 8 g starch flour with the same flavor and green food coloring. Plasma levels of the lactate dehydrogenase enzyme (muscle damage Index). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Elaisa test. Plasma levels of the creatine kinase enzyme (muscle damage Index). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Elaisa test. Plasma levels of Interleukin 6. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: IL 6 kit. Total antioxidant capacity (TAC). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Total antioxidant assay kit. Activity of Super oxide dismutase enzyme (SOD). Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Super oxide dismutase assay kit. Glutathione peroxidase enzyme activity. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Glutathione peroxidase assay kit. Plasma level of malondialdehyde. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Malondialdeyde assay kit. Weight. Timepoint: Day 1 after exercise and day 22 after exercise, after a 14-day washout period, again day 1 after exercise and day 22 after exercise (4 time in total). Method of measurement: Seca Scale. Tehran University of Medical Sciences Approved 2017-09-13 Ethics committee of Tehran University of Medical Sciences Ghods street., Keshavarz Blvd Tehran Tehran Iran (Islamic Republic of)