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IRCT20170812035630N1 IRCT 2018-01-21 Vice Challencellor of Mashhad University of Medical Sciences Study of the effect of curcumin on rheumatism Study of the effect of oral curcumin on disease development in patients with rheumatoid arthritis 2017-08-23 anticipated 60 Complete https://irct.ir/trial/26870 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study randomization method based on closed envelopes, Blinding description: Patients give informed consent, but patients don't know whether they are in placebo group, or the original drug group also researcher don't know whether Patients are members of which group شدی the only aware person is analyzer. 3 Arthritis Rheumatoid. Intervention 1: In the intervention group for 3 months, patients treated with curcumin (in the form of nanomissile) are given as 80 mg (80 mg capsules) per day. Intervention 2: In the control group, for 3 months, patients received placebo treatment at a dose of 80 mg (as capsule 80 mg placebo) per day. Undecided - It is not yet known if there will be a plan to make this available
public Afshin Saraf
Ghaem Hospital, Ahmad Abad Street
Mashhad Iran (Islamic Republic of) 99199-91766 +98 51 3801 2753 Afshinsarraf@Hotmail.Com Mashhad University of Medical Sciences scientific Zahra Rezaeiyazdi
Ghaem Hospital, Ahmad Abad Street
Mashhad Iran (Islamic Republic of) 99199-91766 +98 51 3801 2753 rezaeiyazdiz@mums.ac.ir Mashad Universityof Medcal Sciences Iran (Islamic Republic of) Diagnosed with RA according to eular criteria Personal satisfaction no limit no limit Both Curcumin sensitivity Diabetes Pregnancy M06.9 Rheumatoid arthritis, unspecified Treatment - Drugs Placebo In the intervention group for 3 months, patients treated with curcumin (in the form of nanomissile) are given as 80 mg (80 mg capsules) per day. In the control group, for 3 months, patients received placebo treatment at a dose of 80 mg (as capsule 80 mg placebo) per day Disease activity. Timepoint: Before taking curcumin and 3 months after taking curcumin. Method of measurement: Questionnaire DAS 28 ( Disease Activity Square 28). Vice Challencellor of Mashhad University of Medical Sciences Approved 2014-10-01 Ethics Committee of Mashhad University of Medical Sciences Qureshi building, Daneshgah Street Mashhad Razavi Khorasan Iran (Islamic Republic of)