]>
IRCT20191026045244N5 IRCT 2026-08-13 Shahid Beheshti University of Medical Sciences Effect of herbal drug on expulsion of kidney stone To study the efficacy of Urtica herbal oral liquid on expulsion of urinary system stones 2019-09-23 anticipated 190 Complete https://irct.ir/trial/65408 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Eligible patients will be randomly assigned to the intervention group (receiving Urtica extract) or the control group (receiving a placebo) using the Block randomization method with blocks of four. An independent researcher, who has no role in patient recruitment or data analysis, will generate random sequences using the Random Allocation software, Blinding description: To maintain blinding, the study medications were packaged in identical boxes with sequential numbers. The placebo appeared and was labeled identically to the active extract. Participants, investigators handling enrollment and treatment, and the data analyst will all be kept unaware of group assignments, ensuring triple blinding during the entire study. 3 Calculus of kidney with calculus of ureter. Intervention 1: Intervention group: Patient after extracorporeal lithotripsy of kidney or ureteral stones who is being treated with tamsulosin and urtica. Intervention 2: Control group: Patient after extracorporeal lithotripsy of kidney or ureteral stones who is being treated with tamsulosin and placebo. Yes - There is a plan to make this available What will be shared: The information about the type of treatment and the results of intervetion on results of imaging and leb tests will be available. When: The data could be available one year after the published results. To whom: The data will be available for academic faculty members and researchers. Conditions: The control of the data and supplementary analyses of the data could be performed under copyright law. Where to obtain: Urology Nephrology Research Center How to obtain: Request email to first or corresponding author or research manager of UNRC Comments: Data will be available if it used in review articles or in order to citation.
public Dr Abbas Basiri
Pasdaran
Tehran Iran (Islamic Republic of) 1666663111 +98 21 2256 7222 dr.abbas.basiri@gmail.com Shahid Beheshti University of Medical Sciences scientific Dr Maryam Taheri
Pasdaran
Tehran Iran (Islamic Republic of) 1666663111 +98 21 2256 7222 mturo1389@gmail.com Shahid Beheshti University of Medical Sciences Iran (Islamic Republic of) Patients referring to emergency department due to renal colic With evidence of kidney or ureteral stone 5 to 10 mm in abdominal ultrasound or CT scan Without evidence of urinary tract infection With normal kidney function 18 years 75 years Both Persistant renal colic pain Need to any urgent surgical intervention such as ureteroscopy or stent in term of pregnant or lactating women Any symptoms related to drug hypersensitivity Diabetic patients History of urinary system surgery during last years ago Z00.6 Examination for normal comparison and control in clinical research programme Treatment - Drugs Placebo Intervention group: Patient after extracorporeal lithotripsy of kidney or ureteral stones who is being treated with tamsulosin and urtica Control group: Patient after extracorporeal lithotripsy of kidney or ureteral stones who is being treated with tamsulosin and placebo Effect of Urtica herbal drug on the size of expelled stone. Timepoint: 6 weeks. Method of measurement: abdominopelvic ultrasound or CT. Effect of Urtica herbal drug on the time of stone expulsion. Timepoint: 6 weeks. Method of measurement: questionnaire. Effect of Urtica herbal drug on pain severity during stone expulsion. Timepoint: 6 weeks. Method of measurement: visual analogue scale. Effect of Urtica herbal drug on serum creatinine. Timepoint: 6 weeks. Method of measurement: serum creatinine measurement. Effect of Urtica herbal drug on liner function test. Timepoint: 6 weeks. Method of measurement: Measuement of liver tests (ALT, AST). Shahid Beheshti University of Medical Sciences Approved 2019-09-15 Urology Nephrology Research Center Pasdaran Tehran Tehran Iran (Islamic Republic of)