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IRCT20221113056487N1 IRCT 2023-11-26 Ilam University of Medical Sciences Assessing the Efficacy of Chitosan-Based Facial Masks in Acne Treatment CFM Assessing the Hydrating and Antimicrobial of Chitosan-based Facial Mack for the Treatment of Acne Vulgaris Patients 2023-12-12 anticipated 30 Complete https://irct.ir/trial/73699 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: This study aims to examine the effectiveness of Chitosan 0.5% face masks in improving acne by conducting a half-face study design. In this design, one half of the face receives treatment with a face mask, while the other half undergoes routine treatment. By comparing the two areas, we can evaluate the specific impact of the face mask on acne improvement. The study will involve a sample of participants with moderate acne. Each participant will have their face divided into two halves: the left side and the right side. One side will be treated with a face mask, while the other side will follow a routine treatment. All participants divided into two groups with 15 members. The participants will be instructed to apply the face mask to the designated half of their face according to the provided guidelines. Treated half of face is persist during study. The study will run for a period of six weeks, during which the participants will be monitored closely. Regular evaluations will be conducted to assess the progress of acne improvement on both sides of the face. The evaluations will include visual examination, as well as the use of standardized acne severity scales to quantify the changes. The participants will also be asked to report any subjective improvements, such as reduced redness, inflammation, and overall skin texture. N/A Moderate-Acne Vulgaris. Intervention group: Recipient of the mask of magnetic nanoparticles conjugated to chitosan-betaine. The mask contains 97.5% Chitosan solution (0.5%) and 2.5% essential oil and menthol.. Yes - There is a plan to make this available What will be shared: Photos taken in the first days and every two weeks. When: 2026 To whom: Vice-Chancellor for Research and Technology Affairs Conditions: To clarify and use data to create artificial intelligence software Where to obtain: Vice-Chancellor for Research and Technology Affairs How to obtain: Written request to the Vice President of Research and Technology, Ilam University of Medical Sciences Comments:
public Mohammd Hossein Haddadi
Banganjab Ave., Pajohesh Blvd., Ilam university of medical science
Ilam Iran (Islamic Republic of) 6931678588 +98 21 8670 5503 haddadi841@gmail.com Ilam University of Medical Sciences scientific Mohammad Hossein Haddadi
Banganjab Ave., Pajohesh Blvd., Ilam university of medical science
Ilam Iran (Islamic Republic of) 6931687588 +98 21 8670 5503 haddadi841@gmail.com Ilam University of Medical Sciences Iran (Islamic Republic of) Moderate-Acne Vulgaris Patients 12 years 65 years Both Pregnancy and Breastfeeding Autoimmune diseases and systemic diseases Rosacea or Dermatitis Severe acne vulgaris L70.0 Acne vulgaris Treatment - Other Intervention group: Recipient of the mask of magnetic nanoparticles conjugated to chitosan-betaine. The mask contains 97.5% Chitosan solution (0.5%) and 2.5% essential oil and menthol. Reduce skin fat. Timepoint: 6 Weeks. Method of measurement: Abnormal shine of the skin, photography, presence of acne. Average number of acne lesions. Timepoint: The average number of acnes is measured on the first day and then every two weeks. Method of measurement: Observational. Average number of comedones. Timepoint: The average number of comedones is measured on the first day and then every two weeks. Method of measurement: Observational. Average number of inflamed papules. Timepoint: The average number of inflamed papules is measured on the first day and then every two weeks. Method of measurement: Observational. The rate of recovery of lesions. Timepoint: Every two weeks. Method of measurement: Observational. Satisfaction score of mask use. Timepoint: The end of study. Method of measurement: Questionnaire form of lay et al. Satisfaction score of skin fat mask. Timepoint: The end of study. Method of measurement: Questionnaire. Vice-Chancellor for Research and Technology Affairs, Ilam University of Medical Science. Approved 2023-01-09 Research Ethics Committees of Ilam University of Medical Sciences Banganjab Ave. Pjohesh Blvd, Ilam university of medical science Ilam Ilam Iran (Islamic Republic of)