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IRCT20240108060648N1 IRCT 2024-02-12 The university of Tabriz effect of circuit training in side effects of aging The effect of 8 weeks of circular training on serum levels of Brain-Derived Neurotrophic Factor and Nerve Growth Factor in elderly women 2024-03-04 anticipated 30 Complete https://irct.ir/trial/74903 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: The participants will be divided into two groups: a control group and a training group. The effect of the independent variable will be compared between the two groups, one with intervention and one without, Randomization description: The sealed envelope method will be used. In this way, random numbers will be placed inside sealed envelopes. The patient's number will be written on each envelope, and the patient's names will be listed in order. Finally, envelopes will be opened and patients with an even number will be assigned to the training group, while those with an odd number will be assigned to the control group. N/A aging. Intervention 1: Intervention group: They will engage in circuit training 2 or 3 times a week (2 times initially and up to 3 times later) for eight weeks. Then, they will do stretching exercises for the major muscle groups and rotational movements. At the end of the workout, a 10-minute cool-down session was performed, involving stretching exercises. The exercises included standing on the toes, lifting the side of the thigh, opening the knee, bending the knee behind the chair, standing stomach movement (folding the leg towards the stomach or hip flexion), lateral flexion of the spine, Incline Dumbbell Curl, hip extension behind the chair, squat in front of the chair, push up next to the wall, walking, front chest pull-up, or horizontal arm pull-up movement. Intervention 2: Control group: This group will not do any intervention. Yes - There is a plan to make this available What will be shared: I will share the data with other researchers after completing the study with the participants while ensuring privacy. When: After printing and finishing the research, I will provide the data to the researchers. To whom: Researchers and people who use data for scientific advancement. Conditions: I will make it available to researchers to improve science. The data should be used anonymously and should not be misused. Where to obtain: Refer to the email of the responsible author. How to obtain: At first, it should be requested from the University of Tabriz and the supervisor, and then the responsible author will provide them to the researchers. Comments:
public Fatemeh Baharavar
No 77, babaee 2, parvaz
Tabriz Iran (Islamic Republic of) 5167769811 +98 41 3386 2932 baharavar.f@tabrizu.ac.ir The university of Tabriz scientific Fatemeh Baharavar
No77, babae2, Parvaz square
Tabriz Iran (Islamic Republic of) 5167769811 +98 41 3386 2932 baharavar.F@tabrizu.ac.ir The university of Tabriz Iran (Islamic Republic of) Age range 60 to 70 Not taking medicine and supplements Not having a specific disease The doctor must approve the desired sports activity. 60 years 70 years Female Having an underlying disease Having skeletal disease Prevention Prevention Intervention group: They will engage in circuit training 2 or 3 times a week (2 times initially and up to 3 times later) for eight weeks. Then, they will do stretching exercises for the major muscle groups and rotational movements. At the end of the workout, a 10-minute cool-down session was performed, involving stretching exercises. The exercises included standing on the toes, lifting the side of the thigh, opening the knee, bending the knee behind the chair, standing stomach movement (folding the leg towards the stomach or hip flexion), lateral flexion of the spine, Incline Dumbbell Curl, hip extension behind the chair, squat in front of the chair, push up next to the wall, walking, front chest pull-up, or horizontal arm pull-up movement. Control group: This group will not do any intervention. Plasma nerve growth factor level in the elderly. Timepoint: Before and 48 hours after doing exercise. Method of measurement: Nerve growth factor concentration will be measured by blood sampling and by ELISA method and using kits with a sensitivity of 8.7 pg/ml, Promega brand, catalog number 7631G. Brain-derived neurotrophic factor will be assessed in the elderly population. Timepoint: before and 48 hours after doing the exercise. Method of measurement: The serum concentration of brain-derived neurotrophic factor will be measured by blood sampling and by ELISA using kits with a sensitivity of 15.6 pg/ml, Promega brand, catalog number 7611G. Quality of life. Timepoint: It will be done two times, once before the protocol and once 48 hours after the completion of the protocol. Method of measurement: The World Health Organization's quality of life questionnaire will be used to measure the quality of life. People's physical fitness will be measured. Balance factors, cardiovascular endurance, muscle endurance, and body composition will be assessed to determine their effectiveness. Timepoint: It will occur twice, once before the protocol and once 48 hours later. Method of measurement: Functional tests for physical fitness: (stork tests to measure balance, 250-meter test to measure cardio-respiratory endurance, two minutes of walking to measure muscle endurance) and for body composition, the body mass index formula, which is weight divided by the square of height, will be used. The university of Tabriz Approved 2023-08-19 ethic committee university of Tabriz No. 77, babaee2 Ave, Parvaz Tabriz East Azarbaijan Iran (Islamic Republic of)