IRCT20241006063271N1 IRCT 2024-10-09 Shiraz University of Medical Sciences Investigating the effect of Rosa damascene extract on burns caused by radiation therapy The effect of the traditional medicinal product of Rosa damascene in prevention of radiodermatitis in patients with breast cancer 2024-10-06 anticipated 60 Complete https://irct.ir/trial/79385 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive, Randomization description: Patients will be randomly assigned to one of the two study groups with 1:1 blocks using a random number table (by https://www.random.org), Blinding description: The drug in both the intervention and placebo groups will have the same form and will have a code that another person (other than the people involved in the study) is aware of. Also, the evaluator is not aware of the codes and type of substance available, and based on the code on the drug, they record their evaluation results. 1-2 Dermatitis caused by radiotherapy. Intervention 1: Intervention group: The product containing rose extract based on olive oil (prepared by a pharmacist under the supervision of the Faculty of Pharmacy) will be prepared and will be given in 50 ml jars with a coded label, and they are requested to apply to the desired area once a day for 5 weeks. Intervention 2: Control group: The patients of the placebo group will receive a product containing olive oil (based on the original product - without rosehip extract), which is packaged in the same containers (in 50 ml jars) as the intervention group, with a coded label, and they will be requested to apply to the desired once a day for 5 weeks. No - There is not a plan to make this available Justification or reason for not sharing IPD is There is no further information