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IRCT20250927067381N1 IRCT 2025-10-15 Hamedan University of Medical Sciences The effect of Hugo point massage on body pain and fatigue The effect of Hugo point massage on body pain and fatigue in patients with brucellosis admitted to the infectious disease ward of Sina Hospital, Hamadan. 2025-10-23 anticipated 174 Complete https://irct.ir/trial/86455 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Patients will first be selected via convenience sampling and randomly assigned in a crossover design to one of three groups: Group A (pressure applied at the Hugo point), Group B (pressure applied at a sham point), and Group C (control). Randomization will be carried out using permuted blocks of three; specifically, the sequences BCA, ABC, BAC, CAB, CBA, BAC, and ACB will be written on slips of paper and placed into sealed envelopes. Upon obtaining informed consent, each patient will select one envelope and be allocated to the corresponding group according to the letter sequence, Blinding description: Randomization was carried out using permuted blocks of three. The block sequences BCA, ABC, BAC, CAB, CBA, BAC, and ACB were written on paper and placed in sealed envelopes. After obtaining informed consent, each participant selected one envelope; assignment to the corresponding group followed the order indicated by the letters. Participants remained unaware of their group allocation. N/A brucellosis. Intervention 1: Intervention Group 1: In this group, in addition to routine post-treatment care, the Hegu point is first identified. A gentle pressure massage is then applied for 30 seconds, with the pressure gradually increased until the participant experiences tingling, numbness, heaviness, and a sensation of stretching in the surrounding area. The thumb is maintained on the point for 1 minute; subsequently, the pressure is progressively released over 30 seconds to fully release the point. Each intervention cycle lasts 5 minutes.The massage is administered intermittently for a maximum of 20 minutes, comprising three 5-minute massage sessions separated by 2-minute rest intervals (i.e., 5 minutes of massage followed by 2 minutes of rest, repeated until the 20-minute limit is reached). Intervention 2: Intervention Group 2: In this group, in addition to routine post-treatment care, pressure massage is applied to a point located outside the Hegu point as follows. First, gentle pressure is exerted on the non-Hegu point for 30 seconds, with the force gradually increased until the participant experiences pronounced tingling, numbness, heaviness, and a sensation of stretching in the surrounding area. Next, the thumb remains in place for 1 minute; thereafter, the pressure is progressively released over 30 seconds to fully release the point. The entire intervention cycle lasts 5 minutes.The massage is administered intermittently for a maximum total of 20 minutes, consisting of three 5-minute massage sessions separated by 2-minute rest intervals (i.e., 5 minutes of massage followed by 2 minutes of rest, repeated until the 20-minute limit is reached). Intervention 3: Control Group: In this group, no acupressure therapy will be administered, and participants will receive only routine post-treatment care. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The release schedule has not yet been determined.
public Reza Rabiei
Hamadan University of Medical Sciences Headquarters, Shahid Fahmideh St.
Hamadan Iran (Islamic Republic of) 6514894294 +98 81 3830 2243 r.rabiei@edu.umsha.ac.ir Hamedan University of Medical Sciences scientific Arezo Karamporian
Hamadan University of Medical Sciences Headquarters, Shahid Fahmideh St.
Hamadan Iran (Islamic Republic of) 6517838695 +98 81 3838 7250 a.karampourian@umsha.ac.ir Hamedan University of Medical Sciences Iran (Islamic Republic of) To be under a doctor's supervision for all patients To be literate in reading and writing in order to complete the questionnaire To be aged 18 and above 18 years no limit Both To have a history of mental disorders based on the patient's medical records To participate in pain reduction programs of other studies To take painkillers other than the ward's routine medication To have a skin lesion at the site of acupressure application To be unwilling to continue cooperation To develop a serious physical problem To receive less than four sessions of training A23 Brucellosis Treatment - Other Treatment - Other Treatment - Other Intervention Group 1: In this group, in addition to routine post-treatment care, the Hegu point is first identified. A gentle pressure massage is then applied for 30 seconds, with the pressure gradually increased until the participant experiences tingling, numbness, heaviness, and a sensation of stretching in the surrounding area. The thumb is maintained on the point for 1 minute; subsequently, the pressure is progressively released over 30 seconds to fully release the point. Each intervention cycle lasts 5 minutes.The massage is administered intermittently for a maximum of 20 minutes, comprising three 5-minute massage sessions separated by 2-minute rest intervals (i.e., 5 minutes of massage followed by 2 minutes of rest, repeated until the 20-minute limit is reached). Intervention Group 2: In this group, in addition to routine post-treatment care, pressure massage is applied to a point located outside the Hegu point as follows. First, gentle pressure is exerted on the non-Hegu point for 30 seconds, with the force gradually increased until the participant experiences pronounced tingling, numbness, heaviness, and a sensation of stretching in the surrounding area. Next, the thumb remains in place for 1 minute; thereafter, the pressure is progressively released over 30 seconds to fully release the point. The entire intervention cycle lasts 5 minutes.The massage is administered intermittently for a maximum total of 20 minutes, consisting of three 5-minute massage sessions separated by 2-minute rest intervals (i.e., 5 minutes of massage followed by 2 minutes of rest, repeated until the 20-minute limit is reached). Control Group: In this group, no acupressure therapy will be administered, and participants will receive only routine post-treatment care. Score on the NRS questionnaire (Numeric Rating Scale for pain assessment). Timepoint: To complete the Numeric Rating Scale (NRS) before and after the intervention. Method of measurement: Numeric Rating Scale (NRS). Score on the Multidimensional Fatigue Inventory (MFI) questionnaire. Timepoint: To complete the Multidimensional Fatigue Inventory (MFI) before and after the intervention. Method of measurement: Multidimensional Fatigue Inventory (MFI). Hamedan University of Medical Sciences Approved 2025-09-20 Ethics Committee of Hamadan University of Medical Sciences Office of Vice Chancellor for Research and Technology, Hamadan University of Medical Sciences (UMSHA), Building No. 4, Shariati Crossroad., Hamadan, Iran. Hamadan Hamadan Iran (Islamic Republic of)