]>
IRCT20250130064571N2 IRCT 2026-09-15 Hamedan University of Medical Sciences Comparison of the Cerebellar Transcranial Alternating and Direct Current Stimulation on Balance تی دی سی اس Comparison of the Effectiveness of Cerebellar Transcranial Alternating and Direct Current Stimulation on Balance in People with Cerebellar Ataxia 2026-11-21 anticipated 36 Pending https://irct.ir/trial/92841 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Randomization description: Participants will be recruited consecutively and randomly allocated to groups using block randomization via a web-based system. Allocation concealment will be ensured through the use of sequentially numbered, opaque, sealed envelopes, Blinding description: The outcome assessor and participants will be blinded to the type of intervention. To maintain participant blinding, participants will be unaware of whether the stimulator is active. To ensure assessor blinding, the stimulation protocols will be administered by the principal investigator, who will not be involved in outcome assessment. 3 Balance. Intervention 1: First intervention: Transcranial direct current stimulation، Anode electrode placement on cerebellum, Cathode electrode placement on right shoulder, 2 milliampere current intensity, 20 minutes of stimulation. Intervention 2: Second intervention: Transcranial alternating current stimulation، Anode electrode placement on cerebellum, Cathode electrode placement on right shoulder, 2 milliampere current intensity, 40 hertz frequency, 20 minutes of stimulation. Intervention 3: Third intervention: Sham transcranial direct or alternating current stimulation, 2 milliampere current intensity only for the first 30 s, Turned off current for the other 20 minutes of stimulation. Yes - There is a plan to make this available What will be shared: Only part of the static and dynamic balance data of individuals can be shared When: The data access period starts 6 months after the publication of the results To whom: For researchers at academic and scientific institutions only Conditions: Ethical approval: Researchers must provide the necessary approval from their institutional ethics committee or the central ethics committee. Non-disclosure agreement: Signing a non-disclosure agreement and maintaining the confidentiality of the data are mandatory. Time limitation: Access to the data will be granted after approval and for 6 months after the publication of the results. Citation of source: In any report, article, or presentation prepared based on these data, the original source of the data must be accurately cited. Privacy protection: Researchers must fully adhere to the principles of protecting participant privacy and anonymizing the data. Where to obtain: Ailin Talimkhani, Assistant Professor of Physiotherapy, Department of Physiotherapy, School of Rehabilitation Sciences, Hamadan University of Medical Sciences How to obtain: Once approved, the anonymized dataset is prepared and quality-checked by the research team. The data is then released either through a secure data-sharing platform or after signing a Non-Disclosure Agreement. Estimated total time is 5–7 working days. Comments:
public Ailin Talimkhani
Department of Physiotherapy., School of Rehabilitation Sciences., Hamadan University of Medical Sciences., Pajuhesh Sq., Shahid Fahmideh Blvd
Hamadan Iran (Islamic Republic of) 6516955373 +98 81 3821 1857 ailintalimkhani@yahoo.com Hamedan University of Medical Sciences scientific Ailin Talimkhani
Department of Physiotherapy., School of Rehabilitation Sciences., Hamadan University of Medical Sciences., Pajuhesh Sq., Shahid Fahmideh Blvd
Hamadan Iran (Islamic Republic of) 6516955373 +98 81 3821 1857 ailintalimkhani@yahoo.com Hamedan University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Individuals with Cerebellar Ataxia Diagnosed by a Neurologist Individuals with no history of neurological diseases, epilepsy, dementia, or psychiatric disorders Individuals with Standing Impairment Scored Between 1 and 4 Based on the Scale for the Assessment and Rating of Ataxia Individuals with Gait Impairment Scored Between 3 and 8 Based on the Scale for the Assessment and Rating of Ataxia 18 years 47 years Both Individuals with a history of neurological, psychiatric, or cognitive disorders. Individuals using medications that affect balance as a side effect. Individuals with uncorrected visual impairments. Participants who withdraw from the study for any reason. Z50 Care involving use of rehabilitation procedures Rehabilitation Rehabilitation Rehabilitation First intervention: Transcranial direct current stimulation، Anode electrode placement on cerebellum, Cathode electrode placement on right shoulder, 2 milliampere current intensity, 20 minutes of stimulation Second intervention: Transcranial alternating current stimulation، Anode electrode placement on cerebellum, Cathode electrode placement on right shoulder, 2 milliampere current intensity, 40 hertz frequency, 20 minutes of stimulation Third intervention: Sham transcranial direct or alternating current stimulation, 2 milliampere current intensity only for the first 30 s, Turned off current for the other 20 minutes of stimulation Static balance. Timepoint: Assessment of static balance at the beginning of the study (before starting the intervention), immediately after completing the real or sham brain stimulation. Method of measurement: Force plate. Dynamic balance. Timepoint: Assessment of dynamic balance at the beginning of the study (before starting the intervention), immediately after completing the real or sham brain stimulation. Method of measurement: Functional test of Timed Up and Go. Hamedan University of Medical Sciences Approved 2026-08-22 Ethics committee of Hamadan University of Medical Sciences Vice-Chancellery for Research and Technology., Hamadan University of Medical Sciences Headquarters., Pajuhesh Sq., Shahid Fahmideh Blvd Hamadan Hamadan Iran (Islamic Republic of)