IRCT20120215009014N620 IRCT 2026-09-14 Hamedan University of Medical Sciences Comparison of the effectiveness of rose oil and fish oil versus placebo in preventing pressure ulcers in patients admitted to intensive care units Comparison of the effectiveness of rose oil and fish oil versus placebo in preventing pressure ulcers in patients admitted to intensive care units: a double-blind randomized clinical trial 2026-09-23 anticipated 66 Recruiting https://irct.ir/trial/93271 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: In this study, random assignment of patients to the intervention and control groups will be performed using block randomization. To achieve this, six sheets of paper will be prepared - two with the name of "Intervention 1," two with the name of "Intervention 2," and two with the name of "Control." These paper sheets will be pooled and placed in a container. Patients will be selected one at a time without replacement, and for each patient, a paper sheet will be randomly drawn from the container. After each draw, the paper sheets will be returned to the container, and the process will be repeated until the desired sample size is reached, Blinding description: The drugs will be administered in coded envelopes. Both the medications and placebos will have the same shape. Consequently, patients will remain unaware of the type of intervention they receive. Moreover, the randomization process will be conducted by a separate individual from the one who examines the patients, ensuring that the examining person remains unaware of the intervention. The person delivering the medications will also be kept blind to the type of interventions. Therefore, the trial will be conducted as a double-blind study. 3 Pressure ulcer. Intervention 1: Intervention Group 1: Application of rose oil to the patient's sacral region three times daily for five days. Intervention 2: Intervention Group 2: Application of fish oil containing omega-3 fatty acids to the patient's sacral region three times daily for five days. Intervention 3: Control Group: Application of polyethylene glycol 400 to the patient's sacral region three times daily for five days. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is It depends on the situation and the results of the study as well as the approval of the financial supporting organization.