The aim of this study is comparing efficacy of two treatment methods including oral azithromycin and cryotherapy in children with cutaneous leishmaniasis caused by leishmania tropica. Sixty six patients below 14 years old (two groups with 33 individuals) that their cutaneous leishmaniasis have been diagnosed by direct skin smear (Giemsa staining method) or skin biopsy and their clinical lesion have longed less than 6 months will enter to study. The first group will be treated with oral azithromycin 10-12mg/kg daily up to 10 days in first session and then it will be repeated during 3 following periods. The second group will be treated with cryotherapy 10-20 s weekly, until the lesion with 1 mm of its surrounding are completely infiltrated. The result will be recorded as changes of lesion indurations basis in each follow up visit. Patients will be followed for 3 months after finishing treatment and lesion indurations and possible side effects will be recorded.