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This study is designed to compare the effects of honey and mefnaid acetate in healing of grade 3 and 4 burn wounds on patients admitted in burn ward. One hundred patients are randomly assigned to intervention or control group. After admission and initial preparing and wound irrigation with normal saline, dressing with a layer of honey or mefnaid acetate on wound will be done twice daily, in the intervention and control group, respectively. Clinical improvement will be evaluated as the granulation tissue area by using visual analog scale on 7 and 21 day and one month after the intervention.
IRCTID: IRCT201008144563N1
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