purpose of study: Determine the effect of Tai Chi Chuan on balance and quality of life in women with Multiple Sclerosis. Study Design: Quasi exprimental-Two group (Intervention & Control)-Randomized-Before & after study. Inclusion criteria: women aged between 20 and 60 years, diagnosed with MS; Expanded Disability Status Scale (EDSS) score was last recorded in the patient's medical records equal to or less than 5/5; absence of other acute or chronic debilitating diseases, such as: pulmonary heart disease, musculoskeletal (joint replacement, etc.), mental or psychological problems (depression, cognitive impairment, etc.). Diagnostic criteria was patient medical records and patient self-expression; absence of pregnancy and signing the informed consent to participate in the study. Exclusion criteria: patients who met the study and inclusion criteria have not been; causing acute and severe recurrent of disease; if the patient began to practice other exercise and any reason that the patient refuse to cooperate. Target sample size: 34 patients. Intervention: Practice Tai Chi Chuan exercise. Date of intervention: Fall 2012. Duration: 12 Weeks, Twice a week. Outcomes: Measurement of balance & quality of life of MS patients.