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The purpose of this research is study of therapeutic effect of curcumin in clinical signs and quality of life in mild Alzheimer's disease.Trial is randomized , double blinded(for patients) and control with placebo.groups of study are mild to moderate Alzheimer's disease and patients that have psychic disorder become out of study. two groups of 35 patients for 12 weeks in addition to routine treatment , treat by curcumin capsule (500 mg twice a day) or placebo.Major indexes at the beginning and end of study are MMSE and quality of life questionnaires.