Study aim: Determining and comparing the impact of an educational program on air traffic management for children using two methods: role-playing combined with simulation and serious play based on escape rooms, on the knowledge and performance of students at Guilan University of Medical Sciences with an interdisciplinary teaching approach. Design: Randomized controlled trial with a control group, using parallel groups, unblinded, randomized, on 90 students. Sealed Envelope Ltd's online randomization service was used for randomization. Settings and conduct: The context for conducting the research and collecting data is provided by the Shahid Beheshti School of Medicine, Nursing, and Midwifery in Rasht, and the Clinical Skills Center of the Shahid Beheshti School of Nursing and Midwifery in Rasht. Participants/Inclusion and exclusion criteria: Entry criteria:  Willingness to participate in research. Students in the 6th and 7th years of the professional doctoral program in medicine 4th year nursing students 2nd, 3rd, and 4th year students of the continuous bachelor's program in emergency medicine Exit criteria:  Absence in any of the training sessions.  Incomplete completion of the information gathering tools in any of the screening stages, pre-test, or post-test. Intervention groups: Intervention Group One (Role-Playing with Simulation)Intervention Group Two (serious game based on escape room) Control Group Main outcome variables: Role-playing group with simulation Serious game group based on escape room Control group Knowledge Performance Satisfaction with the teaching method