Study aim: Comparison the Effectiveness of Mindfulness Based Cognitive Therapy and Short-Term Axis-based treatment as Therapeutic Supplements with Drug Therapy in Improving the Quality of Life in Multiple Sclerosis Patients Design: The present study is a semi-experimental study with pre-test and post-test with control group. The sample size in this study is 60 people, Each group has 20 subjects. Settings and conduct: The statistical population of patients with multiple sclerosis is a recurrent type that will be referred to Mashhad's treatment centers in the second six months of 1396. The statistical sample will be selected from the statistical community in an accessible manner according to the criteria of entry, and then will be randomly assigned to the control and testing groups Participants/Inclusion and exclusion criteria: Entry requirements : Diagnosis of Multiple Sclerosis . Age between18_50Year . Minimum Diploma Education . Being in the Phases of Relapsing Remiting . Conditions of failure to enter : Pass the stage of Relapsing Remiting . Taking psychedelic Drugs . Intervention groups: A group based on knowledge-based cognitive therapy as well as another experimental group will be treated as a complementary treatment based on the short-term solution-based treatment, but the control group will have drug treatment, and all groups will respond to pre-test and post-test at the same time Main outcome variables: Quality of Life