Study aim: Determining the effect of foot reflexology massage on incidence and severity of pain due to muscle cramps in hemodialysis patients Design: Clinical trials with control group and intervention group and randomized Settings and conduct: After approving the research project and writing a written consent from the research vice chair and ethics committee of Islamic Azad University, Tehran Medical Branch, the researcher will go to the selected hospital and, by presenting the letter to the relevant center, will be allowed to enter the research environment, then by referring to the section Hemodialysis of Amir al-Momenin Hospital and Ayatollah Hospital of Esfahani Hospital, patients who have been admitted to the study are selected as samples.Patients' eyes in both groups will be evaluated on the intensity of pain and muscle cramps using a numerical scale of pain and a researcher-made questionnaire Participants/Inclusion and exclusion criteria: Patients with a history of muscle cramp Intervention groups: The intervention included reflexology massage for 3 weeks, three sessions per week for 15 minutes during hemodialysis on the intervention group. The group carries out routine care by nurses in the hemodialysis department. Main outcome variables: muscle cramp