Study aim: Comparison of the mean scores of pain in patients with multiple sclerosis in the aromatherapy group and acupressure group after intervention Design: The study population consisted of patients with multiple sclerosis referred to Rafsanjan Special Disease Center. The sample size was estimated to be 30 individuals. Data collection tools included demographic information questionnaire , self-report form of pain characteristics. Samples were randomly divided into two groups, including aromatherapy and acupuncture. In the first group, lavender extract was administered 2% to the patients by fumigation machine. In the second group, acupressure was given to this group of necessary training and interventions Settings and conduct: The study was performed at the Rafsanjan Special Disease Center. Samples were randomly assigned to acupuncture and aromatherapy. In the first group, 2% lavender extract was administered to patients by fumigation device. In the second group, acupressure group received necessary training and interventions. Visual Analogue Scale checklist was used before and after the intervention. Participants/Inclusion and exclusion criteria: The criteria for entering the study include: 1- Having no swelling and numbness at the Hugo point 2. Having periodic examination records at the Rafsanjan Special Medical Center 3. Not having a history of using acupressure for any purpose Exclusion criteria: 1. Reduced level of consciousness 2. The patient's unwillingness to continue cooperation . Intervention groups: Interventions were performed in two groups of acupressure and aromatherapy. Samples were assigned to two acupressure and aromatherapy groups by random sampling. In the first group, lavender extract of 2% was administered to the patients by inhalation apparatus. In the second group, acupressure was given to this group of training and interventions Main outcome variables: knee pain