Study aim: Determining the comparative effect of cold spray and acupressure on pain during venipuncture in hospitalized children Design: Clinical trial with control group, with parallel, randomized groups, 123 children Settings and conduct: Approval of the research plan in the university ethics committee. At the beginning of the study, complete the demographic characteristics checklist and the Visual Analogue Scale. Intervention group 1: Cold spray: Interventions will be carried out according to the protocol, for 8 weeks and 1 day per week. Intervention group 2: Acupressure: Interventions will include; 8 sessions, each session will last 1 hour and 1 session per week, and will be carried out for a total of 8 weeks according to the protocol. During and after the venipuncture procedure, the visual analog scale will be completed again. The place of the intervention will be the special venipuncture room in each department. Participants/Inclusion and exclusion criteria: Admission requirements: Being 6-12 years old. Conditions of non-entry: taking painkillers within 3 hours before or during the study. Intervention groups: Intervention group 1: Cold spray: Spray puff for 5 seconds at a distance of 15 cm to an area of ​​approximately 5 cm2 at the operation site. After fixing the tourniquet and disinfecting the skin for 60 seconds, intravenous injection will be performed. Intervention group 2: Acupressure: It will be performed from point P6 according to the protocol, which will be performed in 1 session and each session will last 10 minutes. Control group: non-intervention: this training group will not be given. Main outcome variables: Pain during venipuncture