Study aim:
The study of the effect of herbal drug phyllanthus Emblica, Rosa Damascene, Althaea Officinalis and Honey in patient with covid 19 referring to Ahvaz Jundishapur University of Medical Science hospitals.
Design:
Randomize double blind clinical trial, with control group, with a sample size of 60 people, with parallel groups, Phase 3 of Clinical trial
Settings and conduct:
The place of the study is Ahvaz University of medical science hospitals, simple sampling of patients with random allocation, double blind clinical trial, used drug and placebo, Supervisor and participants are blind
Participants/Inclusion and exclusion criteria:
Inclusion criteria: 1. Age ≥18 years 2. Polymerase chain reaction (PCR) test confirmed infection with COVID 19. 3. Lung involvement in imaging 4. Hospitalized 5. Less than 8 days since illness onset 6. Willingness of study participant to accept randomization to any assigned treatment arm. 7. Must agree not to enroll in another study before 28th day of this study. Exclusion Criteria: 1. Receipt of any another experimental treatment 2. Severe liver disease 3. Known allergic reaction to drugs 4. Severe renal disease 5. Pregnant or breastfeeding women 6. transferred to another hospital
Intervention groups:
They receive medicine. 1000 g of amla plant powder soaked in rose water is mixed with 500 g of marshmallow powder, 500 g of rose powder and 5 kg of honey and then packed in 150 g cans. Control group: Placebo will receive 3500 g of starch powder. It mixes well with 3,500 grams of sugar syrup and is packaged in 150-gram cans, and patients take 5 grams of the drug or placebo every 6 hours.
Main outcome variables:
virus polymerase reaction, fever,respiratory rate, dyspnea, chill, cough, Body Pain, Weakness, chest CT scan, lymphocyte blood count, neutrophil blood count, platelet, C _ reactive protein, erythrocyte sedimentation rate
IRCTID: IRCT20200404046937N3