Study aim: Determining the effect of spiritual care based on Ghalbe Salim on anxiety related to COVID-19 in working women of Larestan offices in 2020 Design: Randomized Clinical Trial with control and intervention group. parallel groups without blindness. on 28 working women in Larestan offices Settings and conduct: The present study was performed on working women in Larestan offices . Participants/Inclusion and exclusion criteria: Admission requirements: Be a woman and work in government offices. Exit conditions: Do not have the necessary conditions to do homework and accompany the program. Intervention groups: The program of spiritual intervention based on Ghalbe Salim was based on Islamic verses and hadiths and approved by religious experts. This program included presenting solutions in four areas as follows : A) Communication with God B) Communication with yourself C) Communication with others D) Relationship with nature and environment After identifying the members of the intervention group, 6 virtual 60-minute sessions were held. The agenda of the meetings was as follows: 1.Expressing the content identified by researchers in a variety of ways, including playing short videos, audio and text for 20 to 30 minutes 2.Specify the task of the next session includes writing your opinion on a specific spiritual subject, doing a practical task such as doing a particular act of worship and expressing your feelings about it, and so on. 3.Questions and answers and summarizing the contents and feedback of the homework of the previous session for 20 minutes. The control group was selected from the same participants who had the inclusion criteria.The control group did not receive any intervention. Main outcome variables: After the intervention, the Corona Anxiety Scale Questionnaire was completed.