Study aim: the effect of nursing process based on the goal attainment theory on activities of daily living & quality of life in individuals with multiple sclerosis Design: Experimental clinical trial on 70 patient, quad permutation randomization method. Settings and conduct: the research environment is Hamedan MS Association . The nursing process is based on the theory of goal achievement in the experimental group. Participants/Inclusion and exclusion criteria: Have at least primary education, age limit of 20 to 50, at least 6 months have passed since the diagnosis, diagnosis with relapsing and remitting multiple sclerosis, not being in acute phase of disease, not having other physical and mental illnesses (based on the person's medical history), able to speak Persian, has a balanced mental state and is aware of time and place. Exclusion criteria include: any problem that leads to termination of participation at any time during the study (such as death, transfer to another city) and the patient should be in the condition of the crisis during the study . Intervention groups: experimental group, will have at least one face-to-face session to review the patient and prioritize goals and care planning for each patient, then the follow-up will be done for 4 consecutive weeks, by phone or through social networks. The control group, no interventions are performed and they are subject to the routine program of the MS Association. Main outcome variables: Quality of life and activities of daily living