Study aim: Determining the effect of Osvix drug on tinnitus and headache in patients with stenosis or hypoplasia of the transverse venous sinus. Design: 42 available patients were included in the study and were treated with 75 mg of Osvix daily for one month, and before and after the intervention, they were evaluated for the severity of disability caused by headache and tinnitus. Settings and conduct: 42 available patients referred to the neurology clinic of Imam Reza Hospital with symptoms of tinnitus and headache, diagnosed by a neurologist in vascular imaging as having stenosis or hypoplasia of the transverse venous sinus, were included in the study. They are given 75 mg of Osvix daily, and before and after the intervention, they are evaluated in terms of the severity of disability caused by headache and tinnitus by a questionnaire. Participants/Inclusion and exclusion criteria: Age between 18 and 68 years Having tinnitus and headache, and unilateral or bilateral stenosis or hypoplasia in the transverse venous sinus evident in MRV The absence of known neurological diseases leading to tinnitus, Pregnancy and breastfeeding Intervention groups: 42 patients were included in the study and were treated for one month with 75 mg of Osix daily. Main outcome variables: Reducing the sensation of Tinnitus and headache