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Study aim: The aim of this study is to compare the effectiveness of Unified Transdiagnostic Intervention and Acceptance and Commitment Therapy on sensory processing sensitivity, interpretive bias, and experiential avoidance in individuals with functional seizures. Design: This study is a randomized quasi experimental trial with parallel groups and a control group involving 45 participants. Participants will be allocated to three groups using block randomization with a 1:1:1 allocation ratio. Outcome assessors will remain blinded to group allocation. The study phase is not applicable. Settings and conduct: The study will be conducted at Razi Psychiatric and Neuropsychological Center in Tabriz, Iran. After screening and obtaining informed consent, participants will be randomly assigned to study groups. Assessments will be conducted at pretest, posttest, and three month follow up by outcome assessors blinded to group allocation. Participants/Inclusion and exclusion criteria: Individuals with functional seizures aged 18 to 55 years, diagnosed by a psychiatrist or neurologist, with stable medication during the previous three months, ability to read and write Persian, and informed consent will be included. Individuals with severe psychotic disorders, severe neurological comorbidities, inability to participate regularly in treatment sessions, or changes in psychiatric medications during the study will be excluded. Intervention groups: The first group will receive Unified Transdiagnostic Intervention in 12 weekly group sessions. The second group will receive Acceptance and Commitment Therapy in 8 weekly group sessions. The control group will remain on a waitlist and will not receive structured psychological intervention during the study period. Main outcome variables: Sensory processing sensitivity; interpretive bias; experiential avoidance
IRCTID: IRCT20251124068098N1
  1. The Effectiveness of Unified Transdiagnostic Interventions on Experiential Avoidance, Emotion Regulation, and Treatment Sustainability in Individuals Undergoing Substance Abuse Treatment
  2. The Effectiveness of the Unified Protocol for Transdiagnostic Treatment on Symptoms and Psychological Indicators of University Students with Health Anxiety Comorbid with Other Emotional Disorders: A Randomized Controlled Trial
  3. The effectiveness of acceptance and commitment therapy on experiential avoidance, self-compassion, and fear of recurrence in cancer patients
  4. The Effectiveness of Integrated Transdiagnostic Treatment on Improving Symptoms and Emotional Indicators in Individuals with Internet Addiction Comorbid with Other Emotional Disorders: A Randomized Controlled Trial
  5. Psychological interventions for migraine: A Randomized Controlled Trial Comparing the Efficacy of Intensive Short-Term Dynamic Psychotherapy, Modified Schema Therapy, and Acceptance and Commitment Therapy on Rumination, Experiential Avoidance, Pain severity and Quality of Life in Migraine Patients.
  6. Comparing the effectiveness of reality therapy with acceptance and commitment therapy on craving, self-control, hope, and distress tolerance in male substance abusers undergoing treatment in residential addiction treatment centers
  7. The study of the efficacy of the Transdiagnostic Treatment of the Unified for the Improvement of Comorbid Psychological Disorders (Depression, Anxiety and Health Anxiety), Fatigue and Quality of Life in Patients with Multiple Sclerosis (Ms)
  8. Investigation the effectiveness of acceptance and commitment group intervention on sexual avoidance, sexual satisfaction, marital happiness, and quality of life in individuals with sexual interest/arousal disorder
  9. A comparison of the effectiveness of acceptance and commitment therapy (ACT) and unified transdiagnostic treatment (UP) in psychological distress, meta-emotion beliefs, acceptance and post-traumatic growth in colorectal cancer patients comorbid with stress
  10. Comparing the effectiveness of acceptance and commitment therapy with mindfulness-based cognitive therapy on psychological flexibility, life satisfaction, life expectancy, and stress in elderly people with type 2 diabetes
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