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Study aim
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Since no previous studies have compared the efficacy of dexamethasone and lidocaine in preventing the incidence of respiratory complications after extubation in children with a history of reactive airways, this study sought to compare the effects of these two drugs in decreasing the mentioned complications in children with reactive airways.
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Design
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This randomized double-blind clinical trial will conduct at Imam Hossein Pediatric Hospital
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Settings and conduct
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The double-blind design will ensure by keeping the patient, the person who injected the medicines, and the data collector unaware of the group allocations.
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Participants/Inclusion and exclusion criteria
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healthy one-six-year-old ASA I/ASA II candidates of inguinal hernia repair who had a history of reactive airways or cold symptoms in the past six weeks were included. The exclusion criteria were fever, productive cough, rhonchi in lung auscultation, prolonged surgery (longer than one hour), bleeding, and any complications of the surgery.
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Intervention groups
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An anesthesiologist prepar equal volumes of medications in similar syringes. Before the induction of anesthesia by the nurse, the first, second, and third groups receive intravenous dexamethasone (0.2 mg/kg), intravenous lidocaine (1 mg/kg), and placebo (normal saline with similar volume),
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Main outcome variables
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After patient transfer to the post-anesthesia care unit (PACU), the researcher record SPO2, MAP, heart rate, and respiratory complications (cough, laryngospasm, bronchospasm, every 15 minutes. Moreover, the same parameters will evaluate every two hours during the first six hours of the patient’s stay in the ward.