The effect of 12 weeks of adding music therapy to exercise at home on the physical and cognitive performances of Alzheimer's patients

Evaluation of the effect of 12 weeks of adding music therapy to exercise at home on the physical and cognitive performances of patients with Alzheimer's disease

In a clinical trial with the control group, with two parallel experimental groups, the sample size was estimated based on G-Power software estimates of about 15 individuals in each group. (In this study, a total of 45-48 people will be selected as subjects). The single-blind study, assignment of subjects in groups will be done randomly by a third person

The trainer will communicate with each patient individually via video call and the patient will do the exercises at the same time with the trainer at their home. For the music-exercise group, non-verbal and traditional Iranian music and sonatas from Mozart will be played simultaneously with training. in this study, single blinding will perform and the person who will take the tests and analyze data would be kept blind to the groups. The tests will be taken at Roozbeh Hospital and Kharazmi University.

inclusion criteria: age between 50 to 70, mild to moderate disease degree, having one companion at least, ability to do daily routines exclusion criteria: Any anomalies or defects or physical injuries, having severe Alzheimer's disease, the physician discretion

1-Intervention group 1 (exercise + music) includes Alzheimer's patients who receive exercise at home with music. 2-Intervention group 2 (exercise without music) includes patients with Alzheimer's who receive exercise intervention at home without music. 3-The control group includes Alzheimer's patients who do not receive any intervention and continue to live a normal life.

handgrip strength, cognitive status, quality of life, verbal fluency, performance independence, sleep disorders, Chair Stand test.

The third person who was not in the research team will divide the subjects into 3 groups using a simple block random method. Allocating subjects to the study groups (interventions and control) will be done through block randomization using blocks of size 6. This will be by the website (https://www.sealedenvelope.com/simple-randomiser/v1/lists). In each block, four subjects will be from the intervention groups (music group and exercise-music group) and two subjects from the control group, which will arrange randomly. Finally, eight blocks will use.

The person who will take the tests and analyze the data is kept blind to the groups.

For ethical reasons and without permission, personal details will not be published