Comparison of the Efficacy of 12 Weeks of Combined Training with and Without Taurine Supplementation on the Control of adipokines Indices in obese men

Comparison of the Efficacy of 12 Weeks of Combined Training with and Without Taurine Supplementation on the Control of adipokines Indices in obese men

Clinical trial involving four groups: (1) a combined exercise intervention group with taurine supplementation (n=11), (2) an exercise intervention group with a placebo (n=11), (3) a taurine-only supplementation group (n=11), and (4) a placebo-only group (n=11). This is a single-blind, randomized trial.

This study is a single-blind clinical trial designed to investigate obese men in Sanandaj. Forty-four participants recruited from local sports clubs will be randomly allocated to four groups, each comprising 11 individuals: a combined exercise with taurine, an exercise with a placebo, a taurine-only supplementation group, and a placebo-only group. Participants will remain blinded to the contents of the capsules (supplement or placebo).

Inactivity among women aged 23-32 years, with general physical and mental health and a body mass index greater than 30 kg/m², is the focus of this study. Exclusion criteria include the presence of any physical or orthopedic lesions that interfere with exercise performance or hinder the ability to perform quality exercises

In this group, participants will consume one 1 g taurine capsule daily (After breakfast, lunch, and dinner meals) for 12 weeks, supplied by Cayman Chemical, USA. The combined exercises consist of intermittent training with an intensity equivalent to 50–55% of maximum heart rate starting in the first week and progressively increasing to 70–75% of maximum heart rate in week 12, and resistance training with an intensity equivalent to 60% of one-repetition maximum for 12 weeks, 3 sessions per week, and 15 to 25 minutes per session.

Spexin, Asprosin

This study will utilize a simple randomization method. Participants will be randomly divided into four groups: an intervention group receiving combined exercise with taurine supplementation (n=11), an exercise group with a placebo (n=11), a taurine supplementation-only group (n=11), and a placebo-only group (n=11). The randomization will be conducted at the individual level, whereby each of the 44 participating individuals will be assigned to one of the four groups. A computerized sequence will be used to randomly allocate participants to each group. This method ensures high accuracy and reproducibility and minimizes selection bias.The participant allocation sequence was generated using the Block Randomization method. Variable block sizes (e.g., 4 and 8) and a 1:1:1:1 allocation ratio were implemented to ensure a balanced distribution of participants across the four groups. This random sequence was produced by a reliable statistical software or a dedicated computer program. Specifically, the specialized statistical software SPSS version 26 was utilized to generate the allocation sequence.

The present study is a single-blind clinical trial. The single-blinding applies to the taurine and placebo consumption. Participants will read the research protocol during the first session. The supplement and placebo are contained in identical capsules. The capsules will be distributed among the participants. Only the researcher is aware of the contents of the capsules

All data, including the IPD, study protocol, statistical analysis map, informed consent form, clinical study report, and data dictionary, will be published upon completion of the study. This data will be made available in a valid journal article format.

Data will be accessible immediately upon project completion, likely in 1405

This is intended for researchers at academic and scientific

Institutions to support the development of related sciences.

Refer to University of Kurdistan

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