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The purpuse of this study is to evaluate the effect of propolis on glycemic control, Lipid profile, renal function and inflammatory biomarkers in patients with type 2 diabetes. In this placebo controlled double blind clinical trial study, 100 volunteer patients with diabetes mellitus that has Hemoglobin A1c (HbA1c) Test between 5.9-8% and Fast blood sugar between 126-200 mg/dl which only use oral hypoglycemic agents and were diagnosed less than 10 years will be randomly selected and divided to control and treatment groups. Patients in treatment group take 2 capsules of propolis daily whereas in control group 2 placebo capsules will given to patients. Level of fast blood sugare, 2 hours postprandial glucose, hemoglubine A1C , high density lipoprotein, low density lipoprotein, Total cholesterol, triglyceride, serum Insulin, blood urea nitrogen, creatinine, uric acid, alkalin phosphatase and liver enzymes, inflammation factors like TNFa, IL10, IL6, hs-CRP and also height and weight will be evaluated in the beginning and in the end of study. Patients will be asked not changing their physical exercises, diet and life style duration of study which take 90 days. In the end effect of propolis on measured factors will be statistically evaluated and reported.
IRCTID: IRCT2016092730008N1
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